Clinical Immunology
Covid vaccines were well tolerated and no significant cause for concern was reported up in Pakistan’s Covid vaccine surveillance system concluding overall benefits outweighed risks.
Abstract
There have been 39,291 ADRs reported as of 30th Sept 2021, where most reported after the first dose ( n = 27,108) and within 24–72 h of immunization ( n = 27,591). Fever or shivering accounted for most AEFI (35%) followed by injection-site pain or redness (28%), headache (26%), nausea/vomiting (4%), and diarrhoea (3%). 24 serious AEFIs were also reported and investigated in detail by the National AEFI review committee. The rate of AEFIs reports ranged from 0.27 to 0.79 per 1000 for various Covid vaccines in Pakistan that was significantly lower than the rates in UK ( ∼ 4 per 1000), primarily atrributed to underreporting of cases in Pakistan. Finally, Covid vaccines were well tolerated and no significant cause for concern was flagged up in Pakistan’s Covid vaccine surveillance system concluding overall benefits outweighed risks.