Top Research Papers on Genetics PDF

The October 15, 1997, issue of JAMA1 was devoted to genetics and featured articles on genomic screening in late-onset familial Alzheimer disease, BRCA1 sequence analysis, hereditary prostate cancer 1 locus, chromosome 19 single locus, and multilocus haplotype associations with multiple sclerosis, cancer incidence after retinoblastoma, prenatal genetic carrier testing, molecular diagnosis and carrier screening for β-thalassemia, genetic testing in hereditary colorectal cancer, molecular neurogenetics, family history and genetic risk factors, and preparing health professionals for the genetic re...

The tension between content tagging and genetic tagging is solved in favor of the first, which made it necessary to encode a pre-annotated copy of the text to be used in subsequent editions.

A better understanding of both basic and applied plant biology is critical to overcoming a number of challenges currently facing humanity, including combating climate change, world hunger, the production of sustainability energy, and the conservation of biodiversity and ecosystem function.

A better understanding of both basic and applied plant biology is critical to overcoming a number of challenges currently facing humanity, including combating climate change, world hunger, the production of sustainability energy, and the conservation of biodiversity and ecosystem function.

The editorial mandate of G3 was structured to complement and partner with the authors' sister journal GENETICS, and to further its mission to ensure that practicing scientists play a central role in the peer-review process since the sharing of data, ideas, and conclusions is foundational to the practice of science.

The reports of original research that I selected demonstrate the breadth of genetic and genomic research being conducted by nurse scientists and can be categorized by three approaches: gene expression studies, candidate gene association studies using unrelated individuals, and candidate gene mutation discovery studies using related individuals.

The use of natural variation in the genetic dissection of quantitative traits has a long-standing tradition, but recent advances in high-throughput technologies for the quantification of biological molecules have shifted the focus in quantitative genetics from single traits to comprehensive largescale analyses.

The recent development of soybean pangenomes has highlighted the significant structural variation between individuals, together with knowledge of what has been selected for or lost during domestication and breeding, information that can be applied for the breeding of improved cultivars.

The Brisbane Systems Genetics Study (BSGS) is described, a family-based study that will be used to elucidate the genetic factors affecting gene expression and the role of gene regulation in mediating endophenotypes and complex diseases.

The purpose of the book is to present in one location a comprehensive overview of the progress of genetics in the rabbit, with a modern vision that integrates genomics to obtain a complete picture of the state of the art and of the applications in this species.

The paucity of research on cancer genomics on African populations is highlighted, gaps in understanding the underlying genetic causes of, and genomic alterations associated with, cancer among black Africans are identified, and the need for concerted efforts to encourage more research in Africa is discussed.

The pig (Sus scrofa) is the most popular large farm animal in the world and one of the most sought-after agricultural commodities in the developing world.

This article addresses a number of issues, including recruitment of participants, disclosure ofResults, psychological impact of results, insurance and employment discrimination, community engagement, consent for tissue banking, and intellectual property issues.

This poster presents a probabilistic procedure for determining the phytochemical properties of potato Kernel Tolerance and its applications in agriculture and food safety.

In this review important advances in the genetics and genomics of cassava are described.

Current knowledge in genetic factors, gene expression patterns, and protein expression patterns in atherosclerosis research with a special emphasis on microarray technology are summarized.

With a greater reliance on sample-derived data for genetic and genomic research and clinical care, improved standards and informatics for sample procurement, storage, and analysis are required to maximize the value of tissue collection for research participants, investigators, medical centers, and funding agencies.

Well-annotated biospeci-men collections have enabled the recent identification of genes and geneticlocithoughttocontributions for several complex diseases.

Specific elements of informed consent for genetic and genomic research conducted in the United States are explored, and alternative consent models that have been proposed are considered.

Governing major work is offered for the master of science and doctor of philosophy degrees with a major in Genetics and Genomics in fourteen cooperating departments.

Neuregulin 1 (NRG1), an epithelial growth factor protein, located at 8p12, has been identified as being a nucleotide variation of the single-nucleotide polymorphism (SNP), rs833497 located on chromosome 18q21.1 that is associated with schizophrenia.

COGA was designed during the linkage era to identify genes affecting the risk for alcohol use disorder (AUD) and related problems, and was among the first AUD‐focused studies to subsequently adopt a genome‐wide association (GWAS) approach.

The results suggest that the application of small molecule IDE1 into quail P GCs represents a step toward achieving an efficient expansion of the PGCs.

This article documents the personal experiences of an oncology nurse who has worked in cancer prevention and early detection since the 1990s and describes the many changes that have occurred in cancer‐related genetic and genomic care during that time.

A role for genetics in choosing a vegetarian diet is supported and the door is opened for future studies aimed at further elucidating the physiologic pathways involved in vegetarianism.

This paper will discuss some ethical aspects involved in current genetics, specifically, cooperative research between researchers from Brazil and indigenous populations Brasil and more detailed and specific rules for these three special areas were proposed.

The use of Genetic Algorithms to help design a drinking water device with UV Implementation of a Genetic Algorithm for Stereo Refinement and a parameter search procedure using genetic algorithms.

This review describes the advances in genetics, genomics, and the breeding of melon and puts forward some recommendations in these areas.

It is concluded that informed consent is no longer a single document tied to a particular study; it is becoming a dynamic process.

Although presented in the context of the H3Africa Consortium, it is believed the principles described, and the decision flowchart presented here is applicable more broadly in African genomics research.

A tendency of the superiority of Bayesian methods over best linear unbiased prediction (BLUP) in accuracy of selection is shown, but some difficulties on elicitation of some complex prior distributions are investigated.

A novel framework for promoting diversity, equity, and inclusion in genomics research is proposed and can guide investigators in optimizing equitable representation in research and enhancing the rigor of genomics investigation.

The subject of the bulk of Parame calcium research, the ancient Paramecium aurelia species complex, is descended from two whole-genome duplication events that retain high degrees of synteny, thereby providing an exceptional platform for studying the fates of duplicate genes.

For the past 5 years, GWAS in kerotconus has been highly successful, such as three suspected pathogenic genes, RAB3GAP1, HGF, LOX were found and some suspicious mutation sites were related to central corneal thickness.

The aim of the integrated genome research network ‘Genetics of Alcohol Addiction’ is to better understand the genetics of alcohol addiction by identifying and validating candidate genes and molecular networks involved in the aetiology of this pathology.

The development of Genetics and Genomics in the clinical and academic field is shown in this review.

One genetic algorithm based on character encoding to achieve intelligent test paper after analysis the character constraints and requirements of test paper and new solutions-gene transposition in regard to the issue of re-title in test paper are raised.

The study explored the perspectives of genetic and genomic researchers on the sharing of biological samples in international collaborative research and emphasized the importance of respecting cultural values in biobanking research.

This review compared the different studies in genetics and genomics of the hypertension that have been made worldwide and in Mexico with the aim of identifying important genes involved in susceptibility to the development of this pathology.

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This story's focus on DNA patents shows how the law has changed to accommodate (or ignore) developments in genomics.

Sub-atomic phenotyping utilizing hereditary and genomic data will permit early and more exact forecast and analysis of infection and of sickness movement, and guide the advancement of new medications and remedial techniques.

This poster presents a probabilistic procedure to evaluate the ability of the immune system to recognize the presence of infectious disease in animals and to establish an immune response to antibiotics.

The application of linkage mapping, quantitative trait loci analysis, gene family annotation and comparative genomics to study various aspects of the genetic and genomic architecture of eucalypts, a group of Myrtaceous flora that are of significant economic and ecological value worldwide are reported.

Recent advances in the tools available for analysis-assaying transcription, sequence variation, and epigenetic marks on a genome-wide scale-have substantially altered this landscape and implications of these technological advances for current understanding of the genetics and genomics of asthma are considered.

Methods and theories from evolutionary biology, phylogenetics, population genetics and molecular biology have been used by conservation biologists to better understand threats to endangered species due to anthropogenic changes.

It seems that for the majority of the goat breeds genomic evaluation could potentially be implemented with reasonable accuracy within breed, using the current Illumina 50k panel and a large enough training population, while for multi-breed genomic evaluation in goats, a dense SNP panel seems to be required.

The study of the genetic characteristics of clinical trial participants allows a more detailed analysis of the role of gene polymorphisms in terms of both pharmacokinetics and pharmacodynamics of the studied pharmaceuticals.

These studies identify new targets for drugs and design specific antibiotics to provide more accurate treatments to combat infections caused by bacteria.

Biochemical and genetic studies elucidate the multiple roles the Dna2 enzyme plays in order to ensure genomic stability and construct a timeline of protein processing steps required for homologous recombination mediated repair.