login

Cardiac Myosin Activation with Omecamtiv Mecarbil in Systolic Heart Failure

New England Journal of MedicinePublished 13 November 2020Open access
John R. Teerlink, Rafael Díaz, G. Michael Felker, John J.V. McMurray, Marco Metra, Scott Solomon
Citations618
SJR quartileQ1
SJR score19.08
SNIP13.47
View PDF

TL;DR

Among patients with heart failure and a reduced ejection, patients who received omecamtiv mecarbil had a lower incidence of a composite of a heart-failure event or death from cardiovascular causes than those who received placebo.

Abstract

Among patients with heart failure and a reduced ejection, those who received omecamtiv mecarbil had a lower incidence of a composite of a heart-failure event or death from cardiovascular causes than those who received placebo. (Funded by Amgen and others; GALACTIC-HF ClinicalTrials.gov number, NCT02929329; EudraCT number, 2016-002299-28.).

Keywords

Medicine