Screening for Hepatitis C Virus Infection in Adolescents and Adults
JAMAPublished 2 March 2020Open access
Douglas K Owens, Karina W. Davidson, Alex H. Krist, Michael J. Barry, Michael D. Cabana, Aaron B. Caughey
Citations284
SJR quartileQ1
SJR score5.35
SNIP10.71
Generate an AI Snapshot to get a quick, structured summary of this paper.
Study Snapshot
ObjectiveWill appear once the snapshot is generated
MethodsWill appear once the snapshot is generated
PopulationWill appear once the snapshot is generated
Sample sizeWill appear once the snapshot is generated
OutcomesWill appear once the snapshot is generated
ResultsWill appear once the snapshot is generated
LimitationsWill appear once the snapshot is generated
A concise AI-generated summary of the paper will appear here once you click Generate AI Snapshot.
TL;DR
It is concluded with moderate certainty that screening for HCV infection in adults aged 18 to 79 years has substantial net benefit and is recommended for all asymptomatic adults without known liver disease.
Abstract
The USPSTF recommends screening for HCV infection in adults aged 18 to 79 years. (B recommendation).
Keywords
Medicine
Annals of Internal MedicineScreening for Hepatitis C Virus Infection in Adults: U.S. Preventive Services Task Force Recommendation Statement
476 Citations2013Virginia A. Moyer
The Agency for Healthcare Research and Quality commissioned 2 systematic reviews on screening for and treatment of HCV infection in asymptomatic adults, focusing on evidence gaps identified in the previous USPSTF recommendation and new studies published since 2004.
HepatologyToward a more accurate estimate of the prevalence of hepatitis C in the United States
437 Citations2015Brian R. Edlin, Benjamin Eckhardt +3 more
The number of US residents who have been infected with hepatitis C is unknown but is probably at least 4.6 million, although additional sources of potential underestimation suggest that the true prevalence could well be higher.
Clinical Infectious DiseasesRising Mortality Associated With Hepatitis C Virus in the United States, 2003–2013
367 Citations2016Kathleen N. Ly, Elizabeth M. Hughes +2 more
In the United States, hepatitis C virus (HCV)-associated mortality is increasing, and from 2003-2013, the number of deaths associated with HCV has now surpassed 60 other nationally notifiable infectious conditions combined.
Annals of Internal MedicineBlood Tests to Diagnose Fibrosis or Cirrhosis in Patients With Chronic Hepatitis C Virus Infection
366 Citations2013Roger Chou, Ngoc Wasson
Many blood tests are moderately useful for identifying clinically significant fibrosis or cirrhosis in HCV-infected patients.
The American Journal of GastroenterologyACG Clinical Guideline: Liver Disease and Pregnancy
291 Citations2016Tram T. Tran, Joseph Ahn +1 more
This practice guideline provides an evidence-based approach to common diagnostic and treatment challenges of liver disease in pregnant women.
JAMAScreening for HIV Infection
205 Citations2019Douglas K Owens, Karina W. Davidson +16 more
It is concluded with high certainty that the net benefit of screening for HIV infection in adolescents, adults, and pregnant women is substantial and the use of ART is of substantial benefit in decreasing the risk of HIV transmission to uninfected sex partners.
Obstetrics and GynecologyACOG Practice Bulletin No. 86: Viral Hepatitis in Pregnancy
166 Citations2007
Annals of Internal MedicineHepatitis C Virus Infection Among Reproductive-Aged Women and Children in the United States, 2006 to 2014
148 Citations2017Kathleen N. Ly, Ruth Jiles +4 more
The current analysis used NNDSS data to evaluate trends in (rather than the prevalence of) HCV infection in reproductive-aged women and children aged 2 to 13 years from 2006 to 2014, and analyzed 2 of the largest population data sets available in the United States.
MMWR Morbidity and Mortality Weekly ReportIncreased Hepatitis C Virus (HCV) Detection in Women of Childbearing Age and Potential Risk for Vertical Transmission — United States and Kentucky, 2011–2014
135 Citations2016Alaya Koneru, Noele P. Nelson +8 more
Findings highlight the importance of following current CDC recommendations to identify, counsel, and test persons at risk for HCV infection, including pregnant women, as well as consider developing public health policies for routine HCV testing of pregnant women and expanding current policies for testing and monitoring children born to HCV-infected women.
Annals of Internal MedicineScreening for Hepatitis B Virus Infection in Nonpregnant Adolescents and Adults: U.S. Preventive Services Task Force Recommendation Statement
111 Citations2014Michael Lefevre, on behalf of the U.S. Preventive Services Task Force*
The USPSTF concludes that persons at high risk for infection should be screened for HBV infection.
Clinical Infectious DiseasesPopulation-level Outcomes and Cost-Effectiveness of Expanding the Recommendation for Age-based Hepatitis C Testing in the United States
73 Citations2018Joshua A. Barocas, Abriana Tasillo +10 more
One-time HCV testing of persons 18 and older appears to be cost-effective, leads to improved clinical outcomes and identifies more persons with HCV than the current birth cohort recommendations.
JAMAScreening for Hepatitis B Virus Infection in Pregnant Women
67 Citations2019US Preventive Services Task Force, Douglas K Owens +16 more
There is evidence that over time, perinatal transmission has decreased among women and infants enrolled in case management, providing an overall substantial health benefit, and the USPSTF reaffirms its previous conclusion that there is convincing evidence that screening for HBV infection in pregnant women provides substantial benefit.
Clinical Infectious DiseasesEstimation of State-Level Prevalence of Hepatitis C Virus Infection, US States and District of Columbia, 2010
51 Citations2017Eli S. Rosenberg, Eric Hall +5 more
A new approach is demonstrated that synthesizes national seroprevalence and state-level mortality data, yielding first estimates of HCV prevalence for all states, and interpret geographic patterns.
Annals of Internal MedicineHepatitis C Virus Screening and Care: Complexity of Implementation in Primary Care Practices Serving Disadvantaged Populations
33 Citations2019Barbara J. Turner, Andrea Rochat +5 more
Despite a similar framework for STOP HCC implementation, performance varied widely across safety-net practices, which may reflect practice engagement as well as infrastructure or cost challenges beyond practice control.
Obstetrical & Gynecological SurveyScreening for Hepatitis C Virus Infection in Adolescents and Adults: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force
19 Citations2020Roger Chou, Tracy Dana +6 more